ADHS durch mütterliches Amalgam

 Neurobehavioral effects of developmental methylmercury exposure. S G

 Gilbert and K S Grant-Webster


 Methylmercury (MeHg) is a global environmental problem and is listed by

 the International Program of Chemical Safety as one of the six most

 dangerous chemicals in the world's environment. Human exposure to MeHg

 primarily occurs through the consumption of contaminated food such as

 fish, although catastrophic exposures due to industrial pollution have

 occurred. The fetus is particularly sensitive to MeHg exposure and

 adverse effects on infant development have been associated with levels

 of exposure that result in few, if any, signs of maternal clinical

 illness or toxicity. High levels of prenatal exposure in humans result

 in neurobehavioral effects such as cerebral palsy and severe mental

 retardation. Prenatal exposure to MeHg in communities with chronic

 low-level exposure is related to decreased birthweight and early

 sensorimotor dysfunction such as delayed onset of walking.

 Neurobehavioral alterations have also been documented in studies with

 nonhuman primates and rodents. Available information on the

 developmental neurotoxic effects of MeHg, particularly the

 neurobehavioral effects, indicates that the fetus and infant are more

 sensitive to adverse effects of MeHg. It is therefore recommended that

 pregnant women and women of childbearing age be strongly advised to

 limit their exposure to potential sources of MeHg. Based on results from

 human and animal studies on the developmental neurotoxic effects of

 methylmercury, the accepted reference dose should be lowered to 0.025 to

 0.06 MeHg microgram/kg/day. Continued research on the neurotoxic effects

 associated with low level developmental exposure is needed.




Exposure to Methylmercury often occures from methylation of inorganic mercury from amalgam-fillings through gastrontestinal bacteriums (vgl. Björnberg, K.A., Vahter, M., Englund, G.S.: Methylmercury, Amalgams, and Children’s Health. Environmental Health Perspectives 2006 March; 114(3): A149–A150.